Gene Expression Switching of Receptor Subunits in Human Brain Development
Fig 5
A novel CDV pair of serotonin-receptor genes HTR1A and HTR5A.
(A) A diagram of the serotonergic synapse. (B) The gene expression profiles of HTR1A and HTR5A serotonin receptors as measured by [32] in four regions of the human prefrontal cortex: dorsolateral, medial, orbital and ventrolateral prefrontal cortex. (C) The gene expression profiles of HTR1A and HTR5A serotonin receptors as measured by [33] in the prefrontal cortex. (D) Subject to subject correlation, after removing the population effect of age, between the expression levels of HTR1A and HTR5A within two age groups, prenatal (10PCW-birth), and postnatal (0-30Y) in the hippocampus.