High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED
Fig 4
Antibiotic resistance in the human gut microbiome.
RPKM values produced by ShortBRED for antibiotic resistance protein families, summed by class of resistance. Samples in the USA-Global, Venezuela, and Malawi cohorts were profiled by mapping reads to centroids due to their lower sequencing depth. Marker information is listed in Table 2. Samples (columns) were clustered according to Canberra distance and antibiotic resistance families (rows) were clustered according to Euclidean distance.