Network Events on Multiple Space and Time Scales in Cultured Neural Networks and in a Stochastic Rate Model
Fig 8
Slow time-scales inference procedure on ex-vivo data.
Correlation between low-pass filtered network activity f (see Eq 19) and the size of the immediately subsequent network spike plotted against the time-scale τ* of the low-pass integrator for two experimental datasets (different periods—about 40 minutes each—in a long recording). The plot in panel A is qualitatively similar to the simulation result shown in panel A of Fig 7: a peak, although broader and of smaller maximum (absolute) value, is clearly identified and statistically significant (with respect to surrogate data, dotted line). Panel B shows two significant peaks in the correlation plot, a possible signature of two concurrently active fatigue processes, with time scales differing by roughly an order of magnitude. Panel A: same data as Fig 5, panel B.