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Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components

Fig 7

Spread cell compression based on EC = 2.5 kPa and EN = 25 kPa.

The computational simulation results for a) 10%, b) 20% and c) 30% compression are compared against the experimental results from [3]. The spread cell geometry depicted was achieved using a spring constant = 1×10−11 N/m and an influence radius δBM = 3μm for the BM. Very good match between the simulation and the experimental results can be observed.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1004544.g007