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Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components

Fig 5

Cell nucleus calibration.

Comparison between experimental and simulation results for different values for Young’s modulus of the nucleus particles. Experimental data taken from Caille et al. [3]. The behaviour of the nucleus is well represented by the chosen force expressions and corresponding fitted parameters over a large range of deformation.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1004544.g005