Implications of Heterogeneous Biting Exposure and Animal Hosts on Trypanosomiasis brucei gambiense Transmission and Control
Fig 3
Zero-growth isoclines (R0 = 1) of T.b. gambiense under perturbation of specific parameters.
The parameter values used were the median values obtained for the high transmission setting, except for those varied in the analysis. In the left plot, isoclines at different levels of vector mortality are shown, depending on the daily removal rate of infected humans (r) and the proportion of time commuters spend in the high exposure area (ΞΎ). The areas above the isoclines represent values of R0 greater than 1, and below and to the right of the isoclines values smaller than 1. In the middle plot the impact of screening humans in the low risk setting (ra) in combination with screening commuting humans (rb) is shown for different levels of animal to human ratios (A/H1). In the right plot isoclines are depicted along removal rates (r) and tsetse density (V/H) in both areas when animals either do not contribute to transmission (ca = 0) or they can infect tsetse (ca = 0.003).