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Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks

Fig 8

Comparison of gene expression measurements in two repeats of the same biological experiment.

The scatter plot shows the measured fold changes of gene expression in E2 vs. Control treated MCF-7 cells in GSE11324 (x-axis) and GSE51304 (y-axis) experiments. Only genes which passed a FDR cutoff of 0.001 (a) or 0.05 (b) are shown. Although both datasets are of high quality, the absolute values of fold change are only moderately correlated. However, the direction of fold change is consistent for most of the genes.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1004504.g008