Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks
Fig 6
Randomization test to determine whether the core TFs and microRNAs identified in MCF-7 estrogen response GRN were obtained by chance.
The scatter plot compares the core number of a TF in MCF-7 estrogen response GRN (y-axis) with its average core number over 10,000 randomly sampled networks (x-axis). To be comparable the randomly sampled networks contained the same number of TFs and miRNAs as the MCF-7 estrogen response GRN.