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A Dynamic Gene Regulatory Network Model That Recovers the Cyclic Behavior of Arabidopsis thaliana Cell Cycle

Fig 4

Continuous version of the A. thaliana CC Boolean model.

In this graph we show the activity of the CDKA;1-CYCD3;1 and the CDKA;1-CYCB1;1 complexes as a function of the amount of cyclins, and KRP1 inhibitor. The CDK-cyclin activity is the limiting factor to pass the G1/S and the G2/M checkpoints. A little more than two complete CC are shown (upper horizontal axis) to confirm that oscillations are maintained.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1004486.g004