Modeling and Classification of Kinetic Patterns of Dynamic Metabolic Biomarkers in Physical Activity
Fig 6
Flow chart of the selected data analysis and biomarker discovery workflow (according to the workflow described by Baumgartner & Graber, 2008 [42]). Intermediate discovery steps include the technical validation of raw data, preprocessing of data, selection of dynamic biomarker candidates, modeling and characterization of metabolite kinetic patterns, identification of metabolite groups with similar kinetic behavior, specification of observed kinetic shape templates, classification of dynamic biomarker candidates, and subsequently the biochemical interpretation of findings.