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Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data

Fig 12

Cell density and cell size estimation.

Left: The Delaunay triangulation of all segmented nuclei serves to estimate the cell sizes via its dual, the Voronoi diagram. Right: Average cell diameter as a function of distance to the spheroid border. The black curve is the average profile of six images (condition III, T3) with bin size 1μm and the red curve is the gliding average with window size 10μm.

Fig 12

doi: https://doi.org/10.1371/journal.pcbi.1004412.g012