Consistency of VDJ Rearrangement and Substitution Parameters Enables Accurate B Cell Receptor Sequence Annotation

doi:10.1371/journal.pcbi.1004409

Consistency of VDJ Rearrangement and Substitution Parameters Enables Accurate B Cell Receptor Sequence Annotation

Fig 12

HMM N-region topology.

By using four states instead of one, this gives improved discrimination for pairs or tuples of sequences because it does not ignore mutation information within N-regions. Self-transitions for insert states ommitted for clarity.

doi: https://doi.org/10.1371/journal.pcbi.1004409.g012