Consistency of VDJ Rearrangement and Substitution Parameters Enables Accurate B Cell Receptor Sequence Annotation
Fig 11
Overall topology of the HMMs in the V, D, and J segments.
Inserts are shown as a single state for clarity, but are replaced by four states in the actual HMM (Fig 12). Note that we include 5’ V and 3’ D exonuclease deletions as a convenience (dashed lines) to account for varying read lengths.