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Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers

Fig 4

Pathway map enrichments of the curated palmitoylome and enrichment of synaptic proteins for palmitoylated proteins.

(a) The 14 pathway map enrichments that obtained a FDR < 0.001 and FE ≥ 2 plotted by-log (FDR). The FE is displayed to the right of each bar. Venn diagram of genes in the compendium and the synaptic gene list from SynSysNet is shown in (b). The overlap between proteins from neuronal sources versus non-neuronal sources is shown in a Venn diagram in (c).

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1004405.g004