Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data
Fig 3
Comparison of CLUE with alternative approaches.
Raw scores, representing the quality of clustering result for each k, for each method were normalized to be between 0 and 1 (y-axis). The higher the score, the more informative the resulting clustering is. The methods were evaluated based on how accurately they can recover the true number of clusters within a simulated dataset. The yellow line represents the true number of clusters in the simulated dataset, and the red dot denotes the predicted number of clusters in each case.