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How Co-translational Folding of Multi-domain Protein Is Affected by Elongation Schedule: Molecular Simulations

Fig 4

SufI folding networks for refolding (A) and for the codon-based CTF (B).

The refolding network possesses 3284 nodes, while the codon-based CTF has only 820 nodes. The size of nodes represent their probabilities. The darkness of the node represents native-ness. The darker one is closer to the native. Diamonds, triangle, and stars indicate that N-, M-, and C-domains are pre-dominantly unfolded, respectively. When pre-dominantly unfolded domains are no uniquely decided, circles are used.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1004356.g004