Reconciling Estimates of Cell Proliferation from Stable Isotope Labeling Experiments
Fig 5
Proliferation rate estimates from 1 week D2-glucose and D2O labeling in mice.
The average proliferation rate of PBMC and splenocytes, obtained by fitting the kinetic heterogenity model to the data collected during labeling with D2-glucose with conventional normalization (using 0.65 × plasma AUC, filled circles), labeling with D2-glucose with normalization to thymocytes (grey-filled circles) and labeling with D2O with conventional normalization i.e. to thymocytes (open circles). Bars represent 95% confidence intervals; AUC = area under the curve.