Structural Model of RNA Polymerase II Elongation Complex with Complete Transcription Bubble Reveals NTP Entry Routes
Fig 2
Structural validation of the model by MD simulations: Nucleic acids flexibility.
(a) The scheme represents the nucleic acid scaffold used in our simulation (numbers denote nucleotide positions). (b)-(d) The RMSF, per nucleotide position, observed in our MD simulations for: mRNA, template DNA and non-template DNA. Grey background denotes those nucleotides that have been observed in crystallographic structures.