Structural Conversion of Aβ17–42 Peptides from Disordered Oligomers to U-Shape Protofilaments via Multiple Kinetic Pathways
Fig 4
The time evolution of the structure for the 5th run at T* = 0.20 in Fig 1C and 1D. Snapshots are taken at (A) t* = 5, (B) 1244, (C) 2608, (D) 3656, (E) 4233, (F) 5442, (G) 6086, (H) 10454, (I) 11063. See S1 Video. The β-strand contents measured by the STRIDE program are (A) 0%, (B) 12%, (C) 26%, (D) 50%, (E) 48%, (F) 66%, (G) 64%, (H) 74%, (I) 75%. The α-helix content is insignificant in these structures and the remaining portions are coil and turns.