Existence and Control of Go/No-Go Decision Transition Threshold in the Striatum
Fig 4
Decision transition threshold in the striatum.
Mean firing rates of D1 and D2 MSNs populations for different cortical input rates with constant difference between the drives to the two populations (scenario - II cf. Eq 9). The DTT in this case is ≈ 20 Hz. The rasters and PSTH for the spiking activity for D1 and D2 MSNs are shown for two points, before and after crossing the DTT. (A) (top) Rasters for D1 and D2 populations at λCTX = 10.0Hz. (Middle) PSTHs for D1 and D2. (Bottom) Difference between the firing rates of D1 and D2 (i.e ΔMSN). Notice that the firing rate of D1 MSNs is higher than that of D2 MSNs (ΔMSN > 0). At the decision transition threshold, the bias switches from D1 to D2.(B) Same as (A) but at λCTX ≈ 25Hz, where ΔMSN < 0.