Existence and Control of Go/No-Go Decision Transition Threshold in the Striatum
Fig 3
Mechanism of decision transition threshold.
The mechanism of decision transition threshold is explained analytically. (A) ΔMSN plotted for different values of λCTX and λFSI. The dashed line refers to the case of increasing cortical excitation and feedforward FSI inhibition (as also discussed in Fig 2A). However, ΔMSN changes from positive to negative along the rows (keeping λFSI constant and increasing λCTX) and along the columns (keeping λCTX constant and increasing λFSI). (B) Mechanism for scenario I, ‘additive’ input, Refer to Eqs 4–8. ΔMSN = Inpstr + Inpadd plotted for increasing values of λCTX. (C) ΔMSN = λD1 − λD2 as calculated from Eqs 2, 3. (D) ΔMSN plotted for different values of λCTX and λFSI. The dashed line refers to the case of increasing cortical excitation and feedforward FSI inhibition (as also discussed in Fig 2C). However, ΔMSN changes from positive to negative by increasing λFSI for a constant value of λCTX. (E) ΔMSN = D1eff + D2eff plotted for increasing values of λCTX. Mechanism for scenario II, ‘multiplicative’ input. Refer to Eqs 13–14. (F) ΔMSN = λD1 − λD2 as calculated from Eqs 21, 22.