Hi-C Chromatin Interaction Networks Predict Co-expression in the Mouse Cortex
Fig 5
Topological signature of Chromosome 16 CIN.
t-SNE maps of the 200kb-CIN of Chromosome 16. Each point in the map corresponds to a link between a gene-pair which is colored according to (A) Clustering coefficient at small-scale, (B) Co-expression label, and (C) Jaccard index at the medium-scale. (D) and (E) show sub-networks of the CIN surrounding selected gene-pairs (indicated in the 2D maps): (D) B3galt5-Carhsp1 (yellow nodes) with the high clustering coefficient average; and (E) Masp1 and Abat (yellow nodes) with the high Jaccard index. Chromatin interaction and co-expression are shown by solid blue and dashed red links, respectively.