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Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling

Fig 4

Selected minimal model structures, core and complete model.

The compressed selected 16 minimal model structures that can explain the discretized data (Fig 3B) are shown. In addition, the complete model structure (that is the union of models 1–16) and the compressed core model structure are displayed. Arrows represent activating (positive) interactions; blunt-ended lines indicate inhibitory (negative) interactions. In each model, the core model is colored black, while the building block (the set of added candidate mechanisms) is shown in turquoise.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1004192.g004