Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling
Fig 2
Interaction graph master model.
The interaction graph master model was built from literature information. Detailed model documentation can be found in S1–S3 Tables. The core model is given in black, candidate mechanisms are depicted in turquoise. Arrows represent activating (positive) interactions, blunt-ended lines indicate inhibitory (negative) interactions. The measured species are marked with bold borders. The lightning symbol indicates that the respective species was experimentally targeted with a chemical inhibitor or siRNA.