Spatial and Functional Heterogeneities Shape Collective Behavior of Tumor-Immune Networks
Fig 2
Qualitative recapitulation of tumor physiology.
Qualitative behavior of the model is illustrated through snapshots in time from a single run of the HDC model using base parameter values. At each time point post-tumor initiation (in days), spatial distributions of cells (by type), M2S, oxygen, and vasculature are depicted. In this particular run, shortly after the final time point shown, all tumor cells were dead. Numerical ranges spanned by colored scale bars are: M2S (0–4 [pg/LS] x 10–6), oxygen (0–1 [pg/LS]), vasculature (0–40 au).