Loregic: A Method to Characterize the Cooperative Logic of Regulatory Factors
Fig 4
Distributions by logic gate of all gate-consistent human regulatory triples in acute myeloid leukemia.
A—TF-TF-target triplets. The symmetric gate pairs are marked using diamonds on top of bars with identical superscript numbers; B—miRNA-TF-target triplets; C—distTF-TF-triplets. The triplets from B and C have different distributions from A, including notably at symmetric gates because their RF1s are miRNA/distTF. Also, the “T = RF2” gate matches more triplets than any other gate in B and C.