Molecular Dynamics Simulations of the Bacterial UraA H+-Uracil Symporter in Lipid Bilayers Reveal a Closed State and a Selective Interaction with Cardiolipin
Fig. 5
Mutations on the CL binding sites.
Occupancy plots for the location of cardiolipins (CL; green) around UraA. The occupancy was calculated as the average over the multiple coarse-grained simulations of the wild type and the mutated forms of UraA (Mut 1: UraAmut-1-CG, Mut 2: UraAmut-2-CG and Mut 3: UraAmut-3-CG; see Table 1).