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Critical Slowing Down Governs the Transition to Neuron Spiking

Fig 4

Scaling analysis of indicators related to critical slowing down in pyramidal neurons.

a, photomicrograph of a neuron with pyramidal morphology and typical responses to depolarizing and hyperpolarizing currents. b, Recovery rate as a function of ΔI, the distance to the bifurcation point, for all trials combined and fitted exponents averaged over individual trials and for different minimal values ΔImin for normal conditions (right, black markers, standard deviation) and after bath application of tetrodotoxin (right, gray markers, standard deviation). c, Variance. d, Autocorrelation. Grey dashed lines on the left side show power-laws with exponent 0.5 for recovery rate, -0.5 for variance and -0.27 for autocorrelation.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1004097.g004