Mining Host-Pathogen Protein Interactions to Characterize Burkholderia mallei Infectivity Mechanisms
Table 4
Enrichment of Gene Ontology (GO) biological processes in host subnetworks.
LCC represents the number of proteins in the largest connected component annotated with a given term; LIM represents the number of proteins in the largest interaction module for a given term; pGO denotes the probability of the same number of proteins as the LCC being annotated with a given GO term solely through a random selection; pRp denotes the probability that a given number of proteins as the LIM are annotated with a given GO term solely through random selection; pRn represents the probability that a given number of proteins as the LIM are annotated with a given GO term solely through random selection in a random network that has the same degree distribution as our human network. All p-values were assessed using the Benjamini-Hochberg method to meet a maximum false discovery rate threshold of 5% [45]. The table contains only the lowest-level GO terms; the complete data are available in S1 Table.