Exploring Bacterial Organelle Interactomes: A Model of the Protein-Protein Interaction Network in the Pdu Microcompartment
Figure 6
Model of PduV docked onto a PduU hexamer.
(A) Docking calculations predict that the N-terminal region of PduV binds the PduU β-barrel that protrudes from the conserved BMC domain. Binding statistics for the PduU-PduV docking and three control simulations are reported in a separate table (B). Those latter, which included the docking of PduU to a non-cognate GTPase homolog of PduV (labeled PduU-ERA), a truncated version of PduU lacking the beta-barrel docking to PduV (labeled PduU Δ17-PduV), and PduV docking to PduA instead of PduU (labeled PduA-PduV), all had substantially worse binding statistics than the PduU-PduV model.