Exploring Bacterial Organelle Interactomes: A Model of the Protein-Protein Interaction Network in the Pdu Microcompartment
Figure 3
A model of the Pdu interactome.
The Pdu PPI network, inferred from predictions made by the RF classifier in its analysis of coevolution descriptors. Individual Pdu gene products are represented as nodes. Enzymes are shown in light blue, while shell proteins are shown in gray; the shell proteins include several BMC type proteins and a single protein (PduN) from the BMV family presumed to be pentameric vertex proteins. Edges connecting two nodes correspond to predicted PPIs. The numerous PPIs emerging from the PduA node are highlighted in pink. It is not possible to fully convey the likely spatial relationships of all the proteins and enzymes (some of whose locations remain uncertain), but nodes for the shell proteins have been placed at the periphery of the layout to convey their outer locations.