The Formation of Multi-synaptic Connections by the Interaction of Synaptic and Structural Plasticity and Their Functional Consequences
Figure 6
Quantitative estimates of the activities show biological reasonable ordering in a reasonable frequency regime.
(A) Activity confidence regions for intra-layer connections in somatosensory cortex. To obtain quantitative results, we used an input-output-relation (blue line) from an adaptive exponential integrate-and-fire neuron [54] and a calcium-based plasticity rule [24] (see Methods). As in Fig. 5, the activities for layer IV connections are larger than those for layer II connections. The firing frequencies lie in a biological reasonable range. (B) The expectation value of the postsynaptic activity for stimulations within the confidence intervals confirm that experimental data can be reproduced with equal pre- and postsynaptic activity as expected for intra-layer connections.