The Thalidomide-Binding Domain of Cereblon Defines the CULT Domain Family and Is a New Member of the β-Tent Fold
Figure 4
Sequence relationships between proteins of the β-tent fold.
The map shows the probabilities obtained for HMM to HMM comparisons, as implemented in HHpred. Queries are in rows, targets in columns. The proteins are: cereblon - CULT domain of human cereblon; Yippee - Drosophila melanogaster yippee isoform A (AAF48266.1); Mis18 - Schizosaccharomyces pombe Mis18 (CAB72327.2), res. 1–125; RIG-I - PDB: 4A2V; MsrB - PDB: 3HCG; GFA - PDB: 1X6M; MSS4 - PDB: 2FU5; TCTP - PDB: 1YZ1; Duf 427 - PDB: 3DJM.