Integrative Multi-omics Module Network Inference with Lemon-Tree
Fig 4
Kaplan-Meier survival curves for a selection of top hub glioblastoma genes predicted by the Lemon-Tree algorithm.
The top three panels are genes having low-levels gains or high-level amplifications (magenta) compared to normal (blue), the bottom three panels are genes having single-copy loss or homozygous deletions (green) compared to normal (blue). All genes display significant differences between the groups (p < 0.05, see S6 Table for a full list of p-values). Patient with putative gene gains or losses have significantly worse prognosis (lower values on the y-axis). The x-axis on all figures represent the time in number of days.