Highly Loaded Behavior of Kinesins Increases the Robustness of Transport Under High Resisting Loads
Fig 4
The rebinding of the unbound kinesin is depicted.
The unbound kinesin has probabilities to rebind at several binding sites of the MT. PK is the probability to stay in the unbound state, while PA, j−1, PA, j, and PA, j+1 are the probabilities to rebind at the (j − 1)th, jth, and (j + 1)th binding site. kA, j is the transition rate from the unbound state to the bound state at the jth binding site. The values of kAj−1, kAj, and kAj+1 vary over the position of unbound kinesin xu, k with respect to the position of binding sites of the MT. CA is a parameter of the model which denotes the rate of rebinding to a certain binding site when the unbound kinesin is exactly above that site.