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Embryonic Stem Cell Specific “Master” Replication Origins at the Heart of the Loss of Pluripotency

Figure 4

MRT and GC distributions in the four chromatin states for H1hesc and three differentiated cell lines (K562, Gm12878, Nhdfad).

(First row) Boxplot of MRT computed in 100 kb non-overlapping windows per chromatin state. (Second row) Boxplots of GC content computed in 100 kb non-overlapping windows per chromatin state. Same color coding as in Fig. 2.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003969.g004