Glutamate Mediated Astrocytic Filtering of Neuronal Activity
Figure 10
Spectral analysis of model astrocytic [Ca2+]i oscillations by wavelet analysis.
A, Time-frequency analysis of a representative astrocyte showing typical low frequency oscillation (Type I). B, Time-frequency analysis of a representative astrocyte showing typical high increasing frequency oscillation (Type II). C, Histogram of the maximal oscillation of astrocytic populations. Typical patterns are colored and fitted by a Gaussian distribution (Type I cells in blue, and Type II cells in red, total n = 373 cells). D, the distribution of astrocyte oscillation frequencies. Each column corresponds to one astrocyte and contains its oscillation spectrum (binned at 0.02 Hz). Astrocytes are ranked according to their mean oscillating frequency; most oscillate at low frequencies but around one third (right part of the panel) respond to stimulations with frequencies as high as 0.2 Hz, thus matching the experiments (cf. Fig. 4D).