Glutamate Mediated Astrocytic Filtering of Neuronal Activity
Figure 6
Spectral analysis of astrocytic [Ca2+]i oscillation with wavelet analysis.
A, Time frequency analysis of a representative astrocyte showing typical low frequency oscillation (Type I). B, Time frequency analysis of a representative astrocyte showing higher frequency response that increases with stimulation frequency (Type II). C, Histogram of the astrocyte maximal frequency (see Methods). Typical patterns are colored and fit by a Gaussian distribution (Type I cells in blue, and Type II cells in red). D, Distribution of astrocyte oscillation frequencies. Each column corresponds to one astrocyte and shows its oscillation frequency spectrum (binned at 0.02 Hz). Astrocytes were ranked according to their mean oscillating frequency; most of them oscillate at low frequencies but around one third (right part of the panel) responded to stimulations with oscillations as high as 0.2 Hz. (n = 284 cells).