Glutamate Mediated Astrocytic Filtering of Neuronal Activity
Figure 4
Astrocytic response to neuronal activity in the presence of neuronal AMPAR and NMDAR/kainate antagonists, and astrocytic mGluR1 and mGluR5 antagonists.
A, Ca2+ traces of two selected neurons (in red), showing stimulated activity according to a multi-frequency protocol, and seven selected astrocytes (in green) in presence of neuronal AMPAR and NMDAR/kainate antagonists. B, Representative traces of same cells and stimulation protocol as in A, showing no [Ca2+]i elevations in the presence of neuronal AMPAR and NMDAR/kainate antagonists, and astrocytic mGluR1 and mGluR5 antagonists.