Dynamics from Seconds to Hours in Hodgkin-Huxley Model with Time-Dependent Ion Concentrations and Buffer Reservoirs
Figure 5
Time series for single SD excursions in (a), (c) the reduced and in (b), (d) the detailed model. In the reduced model SD is triggered by an interruption of the pump activity for about 10 sec (shaded region). In the detailed model the extracellular potassium concentration is increased by mM after 20 sec (vertical line). In (a) and (b) the time series of the membrane potentials (black lines) are shown. Nernst potentials for all ion species are included to the diagrams as a reference. Ion dynamics are shown in (c) and (d) where extracellular ion concentrations are in lighter color.