Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data
Figure 4
Partially ordered set and induced genotype lattice for mutations associated with resistance to IDV.
A. Poset of the continuous time conjunctive Bayesian network for resistance development to IDV. B. The genotype lattice of mutants induced by the poset in A. The vertices represent the genotypes that are compatible with the poset in A. The predicted levels of phenotypic resistance are color-coded (green = fully susceptible, red = highly resistant). Please see Supplementary Table S2 in Supporting Information for the waiting times of mutations.