Glycolysis Is Governed by Growth Regime and Simple Enzyme Regulation in Adherent MDCK Cells
Figure 7
Impact of in silico GLUT modulation on (A) ATP and (B) pentose phosphate pathway (PPP) production rates.
At total of 1900 model parameterizations (0.025–0.975 quantile of 2000 model parameterizations) were assessed for the GLUT modulation and were derived from the optimal result of each bootstrap run, which was also the basis for estimation of the parameter confidence intervals of Table 2. The colored bars on the right hand show the respective production rate; the black vertical line represents the original GLUT activity of cells of Cult1 at 24 h.