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Reconstruction of the Gene Regulatory Network Involved in the Sonic Hedgehog Pathway with a Potential Role in Early Development of the Mouse Brain

Figure 4

Illustration of Gata3 ChIP-seq binding sites on the selected genes.

Red boxes indicate the binding peak locations called by MACS program. (A) Sufu and Gsk3b in the Shh signaling pathway. (B) Slit2/3 involved in axon guidance. (C) Nfasc, Mapt and Limk1 regulating brain development. (D) Qdpr, Th and Slc18a1 involved in neurotransmitter synthesis and release.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003884.g004