Genome-Scale Metabolic Network Validation of Shewanella oneidensis Using Transposon Insertion Frequency Analysis
Figure 6
Three-way comparison between FBA predictions and TIFA and DEC essentiality calls.
(A) Comparison between FBA and TIFA. (B) Comparison between FBA and direct gene essentiality calls (DEC). The sectors of the comparison matrix show the intersections of FBA essential genes (E), FBA nonessential genes (N) and genes not in the MR-1 model (NA) with TIFA and DEC calls for essential genes (E), nonessential genes (N) and uncalled genes (U). The TIFA essential gene calls that could be alternatively explained by polar operon effects are shown in brackets.