eMatchSite: Sequence Order-Independent Structure Alignments of Ligand Binding Pockets in Protein Models
Figure 6
Performance of eMatchSite, PocketMatch and SiteEngine on the Steroid dataset.
The accuracy of local alignment predictors is compared to that using global sequence and structure alignments for (A) crystal target structures, (B) high-, and (C) moderate-quality protein models. TPR and FPR are the true and false positive rates, respectively; gray area corresponds to a random prediction.