eMatchSite: Sequence Order-Independent Structure Alignments of Ligand Binding Pockets in Protein Models
Figure 4
Performance of eMatchSite, PocketMatch and SiteEngine on the SOIPPA dataset of adenine-binding proteins.
The accuracy of local alignment predictors is compared to that using global sequence and structure alignments for (A) crystal target structures, (B) high-, and (C) moderate-quality protein models. TPR and FPR are the true and false positive rates, respectively; gray area corresponds to a random prediction.