Characterizing Protein Interactions Employing a Genome-Wide siRNA Cellular Phenotyping Screen
Figure 2
Characterization of phenotypic similarity by linear discrimination.
(a-c) Images of cells in which sfrp1, dvl2 or fzd7 were knocked down, respectively. (d) First two principal components (PC 1 and PC 2) of the features for cells with knockdown of sfrp1 and dvl2. (e) First two principal components of the features for cells with knockdown of dvl2 and fzd7. Dotted lines sketch a linear separation.