Dynamic Conformational Change Regulates the Protein-DNA Recognition: An Investigation on Binding of a Y-Family Polymerase to Its Target DNA

doi:10.1371/journal.pcbi.1003804

Dynamic Conformational Change Regulates the Protein-DNA Recognition: An Investigation on Binding of a Y-Family Polymerase to Its Target DNA

Figure 7

MPT changes with the conformational dynamics.

is the strength of the specific native contacts between the LF and F domain in B-state of DPO4. controls the conformational dynamics of DPO4. (A) MPT as a function of . (B) The conformational distribution of the A-, I- and B-state of DPO4 in the US, EC, IS and BS with different . The error bar represents the standard error of the corresponding MPT.

doi: https://doi.org/10.1371/journal.pcbi.1003804.g007