A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells
Figure 8
Schematic diagram of the model.
represents cytoplasmic
concentration, excluding a small local
(whose concentration is denoted by
) close to the
release site (i.e., an
cluster). Upon coordinated openings of the
, SR
(
) is first released into the local domain (
) to cause a rapid increase in
. High local
then diffuses to the rest of the cytoplasm (
), and is eventually pumped back to the SR (
).