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A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells
Figure 6
Comparison of parameter-dependent frequency changes in the stochastic and deterministic models.
All curves are computed at 
except in panel A, which uses a variety of 
. Other parameters are set at their default values given in Table 1. A: as 
increases, 
oscillations in both models increase in frequency. B: as 
influx increases (modeled by an increase in receptor-operated calcium channel flux coefficient 
), so does the oscillation frequency in both models. C: as 
efflux increases (modeled by an increase in plasma pump expression 
), oscillation frequency decreases. D: as SERCA pump expression, 
, increases, so does oscillation frequency. E: as total buffer concentration, 
, increases, oscillation frequency decreases.
doi: https://doi.org/10.1371/journal.pcbi.1003783.g006